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For Wisconsin, a win would bring its first title since 1941. Perennial power Duke last won it all in 2010. The game will tip off at 9:18 p.m. ET.

NPR's Tom Goldman talks to Don Gonyea about the latest upsets and advancements in the men's NCAA college basketball tournament. The women's tournament gets underway Friday, too.

The U.S. and its international partners continue nuclear negotiations with Iran. NPR's Scott Simon speaks to Yale professor Stephen Carter about Iran's position in the Middle East.

Researchers were surprised by what they found when they sandwiched a drop of water between two layers of an unusual two-dimensional material called graphene.

SuperPACs, financed by unlimited but disclosed donations, now appear to be the presidential candidate's new best friend. One backing Marco Rubio is revving up, and Ted Cruz already has four.

A funeral was held Saturday in North Charleston, S.C., for Walter Scott, the man shot and killed while fleeing a police officer. That officer, Michael Slager, has been fired and charged with murder.

The president meets with Caribbean leaders in Jamaica Thursday — and a looming energy crunch in the region is high on the list.

As President Obama unveiled a framework of a deal with Iran on its nuclear program, Congress was out of town. Next week, they're back and could prevent sanctions from being lifted.

In a memo to staff, editor in chief Ben Smith acknowledged that the site had deleted more than 1,000 posts — three of them after complaints from advertisers. Gawker first reported on the deletions.

Former Maryland Gov. Martin O'Malley, who will decide on a presidential run soon, is for a higher minimum wage and wants to increase Social Security benefits even though some would pay higher taxes.