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On the new female-driven TV series, Oh (Sideways, Grey's Anatomy) has landed a darkly comic lead role that she says was 30 years in the making.

The scale of the opioid addiction problem is immense. It has become so widespread, touching so many in states across the country that the administration has begun calling it "the crisis next door."

The core business model of Facebook and other tech companies has revolved around user data and advertising. NPR's Audie Cornish talks with financial analyst Brian Wieser about how — and if — that could change in light of the Cambridge Analytica news.

We look at the implications after House Speaker Paul Ryan announced that he will not seek re-election after three years as the speaker.

An epic throw-down happened on Capitol Hill over the role of the federal government. The topic: the Consumer Financial Protection Bureau, the agency created in the wake of the financial crisis.

The most talked about baseball player so far this season is Los Angeles Angel Shohei Ohtani. He's electrified people with his pitching and hitting. It's an unusual talent to be good at both. But how rare is it?

President Trump's nominee to become the next Secretary of State, Mike Pompeo, appears before the Senate Foreign Relations committee Thursday, hoping for a quick confirmation.

Following President Trump's vow on Twitter to attack Syria and the five days since the alleged chemical weapons attack which prompted the move, no attack actions have been taken.

The U.S. has been pushing China to lower its high 25 percent tariff on imported cars, but most countries zealously protect their domestic auto markets — including the United States itself.

The fashion show, which only women are invited to view, is the newest entertainment opportunity to emerge in the ultra-conservative kingdom.