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The Obama foreign policy team was built around expert knowledge about international situations and cerebral policies on projecting American power. Shadi Hamid of the Brookings Institution writes in The Atlantic that deep knowledge and optimism were no match for real life conflicts like the war in Syria.

Scott Pruitt is promising an aggressive rollback of regulations at the Environmental Protection Agency. NPR takes a look at what he's likely to target and the challenges he will face.

Trump has called the approval process "slow and burdensome" and said he wants to speed it up. NPR's Audie Cornish asks former FDA Commissioner Mark McClellan whether that's feasible.

Climbing drug prices are taking a toll on West Virginia's budget, some state legislators say. Expensive drugs fuel an increase in Medicaid spending, which leaves less money for schools and roads.

The White House is flooded with last-ditch requests for clemency by several prominent applicants including NSA leaker Edward Snowden and former Illinois Gov. Rod Blagojevich.

David Greene and Rachel Martin talk to Christopher Buckley, a former presidential speechwriter, about what it means to see Donald Trump become the de-facto head of the conservative movement.

A new California law regulates how autographed items may be sold. Originally intended to cover sports memorabilia and an apparently thriving market in fake autographs, bookstores are worried it will shut down popular author book signings. Now one of them has filed suit.

President Franklin D. Roosevelt set 100 days as a benchmark for his presidency, and every president since has been measured by that yard stick.

At a meeting in San Francisco, thousands of researchers are pondering how they can influence President-elect Donald Trump's thinking on climate change.

The 2016 presidential race is off to a slow start compared to the last two cycles. But the activity is starting to heat up in Iowa, where official and potential candidates spoke at a GOP dinner.