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In baseball, when your team needs a good batter at the last minute— either due to another batter's injury or just strategy— you enlist the help of a pinch…

NPR's Scott Simon and Tom Goldman discuss the Cubs and the curse, the Paralympic games in Rio, and one wheelchair racer who is stirring up a discussion about euthanasia.

As the U.S. and Russia struggle to bring peace to Syria, civilians are paying the toll. A United Nations report documents a surge of violence in recent months and atrocities are mounting.

Renee Montagne talks to Vali Nasr, author of The Shia Revival, about the escalating disagreement between Iran and Saudi Arabia over the annual pilgrimage to Mecca, which begins on Friday.

On Wednesday, Donald Trump met with Mexican President Enrique Peña Nieto. Hours later, he gave a speech on immigration where he promised to build a border wall and empower a new deportation force. NPR's Robert Siegel speaks with Sean Sullivan, a reporter for The Washington Post, about Trump's stance on immigration.

The aim is to make clinical trial data available to volunteers and scientists, even if a drug or therapy being tested turns out to be a failure. That could help identify serious side effects.

The former senior adviser to President Obama suggested the Democratic presidential nominee should work with, not against, the press in an effort to be more transparent.

CEO John Stumpf apologized for betraying customers' trust in a hearing by the Senate Banking Committee to answer questions about Wells Fargo employees opening unauthorized customer accounts.

The GOP nominee offered reporters cherry cobbler during a stop in North Carolina on Tuesday. But he won't answer questions as to why he changed his belief about where President Obama was born.

Drug resistance is no longer a matter of health. It could have massive implications for the world's economy and food supply.