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A roundup of key developments and the latest in-depth coverage of Russia's invasion of Ukraine.

Because people with Down syndrome are very likely to develop Alzheimer's, they are ideal candidates for experimental drugs meant to halt the disease.

A federal hate crime trial for father and son Gregory and Travis McMichael is scheduled to begin Feb. 7.

Russia's invasion of Ukraine sent ripples beyond the immediate conflict zone, breaking supply chains and creating food shortages as two of the world's biggest food exporters went to war.

The social media company said the billionaire Tesla CEO changed his mind about accepting a board seat after becoming Twitter's biggest shareholder.

The NCAA men's basketball championship will be decided Monday night in Indianapolis. Steve Inskeep talks to John Feinstein about the two finalists, UCLA and Florida. The Bruins are seeking a 12th national title. Florida is in the final for the second time since 2000.

Real estate agents normally command 6-percent commissions of when they sell a house. But discount brokers and the Internet are eroding that cut. Wendy Kaufman reports that agents are returning most of their commissions to buyers to speed sales in areas where the boom is already over.

Mission controllers at the Jet Propulsion Laboratory in Pasadena, Calif., burst into applause as the Reconnaissance Orbiter arrives safely to Mars. Only about two-thirds of NASA's Mars missions have survived. The spacecraft is supposed to gather more information about Mars than all previous missions combined.

Britain has declared it will forgive nearly $17 billion of African debt. Richard Dowden, director of the Royal African Society in London, talks about the debt relief agreement.

Student loan interest rates reset every May. This year, they're on the rise.