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That's the title that Science magazine is bestowing upon the medication called lenacapavir — a twice yearly injectable that prevents infection by the HIV virus.

Duke will be the top overall seed in the men's NCAA basketball tournament. In the women's, the top-ranked UConn Huskies are undefeated and hope to repeat as champions for the first time in a decade.

The U.S. Postal Service's leader says it is set to run out of money in less than a year and may have to stop deliveries because of declining mail volume and what USPS sees as burdensome requirements.

Many people who have lost jobs during the pandemic are still awaiting unemployment checks and are figuring out which bills to prioritize. Experts share unusual advice for these unusual times.

Israel's domestic security agency had Hamas' battle plans for the Oct. 7, 2023 attacks but didn't take them seriously. Prime Minister Benjamin Netanyahu deflected responsibility for the failure.

Water has always been a big part of the Fernald story. In the 1980s, nearby residents got the news: the water they'd been drinking was contaminated with uranium and other waste. Part of cleaning up the superfund site meant making the groundwater and surface water safe, and repairing the damage to the aquifer and the Paddys Run watershed.

Body-acceptance advocate Katie Sturino and Ronald Young Jr., host of the podcast Weight for It, answer listener questions about body image, weight loss drugs and bullying.

The festival expands back to its original home, the Cedar Lee Theatre, in addition to screening films in Playhouse Square.

Ugandan politician and musician Bobi Wine says he was tortured by soldiers. He was allowed to come to the U.S. for medical treatment, but says he's going to return to Uganda, despite the risks.

The Hall of Fame college basketball coach, fired by the University of Louisville in 2017 following recruiting violations, addresses his career and recent headline-grabbing mistakes in a new memoir.