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A confidential government database of drug sales has become crucial to the nationwide opioid lawsuit in federal court in Cleveland. The Automation of Reports and Consolidated Orders System, known as ARCOS, recorded painkiller sales between manufacturers, distributors and pharmacies at a time when overdose deaths surged nationwide.

Many doctors never find out when a patient dies from an overdose. A new study shows that when find out, it can alter the way they prescribe addictive drugs.

Jose Antonio Vargas' new book is a memoir about living in the U.S. as an "undocumented citizen" — a secret he himself didn't discover until he was 16.

Mexico gets a president unlike any in modern history on Saturday. A political maverick who operates without a formal party and relies on populist appeal. He's pitching big plans for the region and wants the U.S. involved.

The new movie stars Charlene deGuzman as a woman finding her way back from rock bottom. It's somewhat comedic, but also based on her own condition and recovery.

Elliott Block's low-power Channel 25 – branded as "WKRP TV" – switched frequencies on Nov. 1, leading some over-the-air viewers to think the station had...

More than two years after the gruesome incident, four people are under arrest for the murders of eight people in Pike County.

Soccer team FC Cincinnati is embracing its new identity, announcing it is officially becoming Football Club Cincinnati as it enters Major League Soccer.

The World Bank predicts climate change may displace 143 million people by 2050. Environmental shifts have caused migration on smaller scales throughout the history of North America, historians say.

Odell Beckham Jr. is about to run a deep route out of New Jersey — straight to Cleveland.The superstar wide receiver is bound for the Browns to be a…