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The White House will be imposing targeted sanctions on Venezuelan President Nicolas Maduro, in response to his efforts to rewrite his country's constitution. This is only the fourth time the U.S. has sanctioned a head of state.

To get the necessary 60 votes to pass health overhaul legislation, Senate Majority Leader Harry Reid must resolve Democrats' disagreements on the public option, abortion, cost and affordability.

Authorities are looking for the North Carolina man they say shot a kindergartner and three others. It's the fourth high-profile incident this week in which apparent mistakes were met with gunshots.

A new study shows widespread testing for heart problems in young athletes helps prevent sudden cardiac deaths. But some say that screening every young athlete for a rare condition could cause more problems than it solves.

Over hours of testimony, the Clintons both denied knowledge of Epstein's crimes prior to his pleading guilty in 2008 to state charges in Florida for soliciting prostitution from an underage girl.

The basketball legend's tear-stained countenance is the sports world's go-to symbol of sadness in defeat. So expect to see a few renditions of the meme after this weekend's NCAA tournament Final Four.

Egypt is investigating several prominent human rights groups. Similar moves are taking place in neighboring countries, dashing hopes of greater freedoms generated by the Arab uprisings.

Secretary of State John Kerry tells NPR's Steve Inskeep that the new U.S.-Russia cease-fire deal in Syria is the best option under the circumstances. Without it, he says, there would be more deaths.

The candidate's physician says she is "healthy and fit to serve as President of the United States." She also takes thyroid medication and blood thinners.

Clinton won big; Trump continued his triumphant streak, with the notable exception of Kasich's win in Ohio; Rubio dropped out after a dismal showing in Florida. What that means, in five stories.