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The closure of a major flu vaccine manufacturer will cause major shortages during the upcoming flu season, say health officials. Before its license was suspended, the Chiron Corp. intended to ship 48 million doses of flu vaccine to the United States. NPR's Richard Knox reports.

The Security Council temporarily moves to Kenya to deliberate on possible solutions to the 21-year-long civil war in Sudan. An estimated 2 million people have died since the war began in 1983. The council will also discuss the continuing crisis in the Darfur region. Hear NPR's Jason Beaubien.

The president plans to nominate one of his closest aides to serve as the next Secretary of State. Condoleezza Rice would replace Colin Powell, who announced his departure Monday. Rice's deputy, Stephen Hadley, would become the national security advisor. Hear NPR's Michele Kelemen.

NASA's Deep Impact spacecraft successfully crashed into Comet Tempel 1 early Monday. Scientists arranged the collision in an effort to learn more about the comet's physical makeup.

Hamas' landslide victory last month brings the group to the forefront of power in the Palestinian territories. Israel refuses to negotiate with Hamas and calls the group a terrorist organization. But many Palestinians see Hamas as a legitimate force fighting Israeli occupation, as well as a source of charity.

A former senior member of the Irish nationalist party Sinn Fein has been found dead. Denis Donaldson, expelled by the party in December after admitting he spied for Britain, had been shot in the head. Melissa Block talks with Gerry Moriarty, Northern Ireland editor for the Irish Times.

Angry over a bill that would crack down on illegal immigrants, marchers support a rival measure that would give legal status to most undocumented immigrants. They're getting a big push from Spanish-language media.

A record-breaking wave of African migrants is inundating the Canary Islands. So far this year, more than 22,000 have reached the Atlantic archipelago that belongs to Spain. Nearly 800 poured in Tuesday, one of the busiest days ever. The migrants know that when they reach the Canary Islands, they are effectively in Europe.

In major cities, a powerful street drug concoction of heroin or cocaine and the painkiller fentanyl is proving deadly. In Wayne County, Mich., which includes the city of Detroit, dozens of people have died from the combination since November, with several in the past week.

With New Jersey's legislature and governor failing to agree on a budget, the state has shut down most of its services. Included in the shutdown are state parks and Atlantic City's casinos, which must have government monitors on site to operate. Steve Inskeep speaks with Brad Linder of member station WHYY.