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The biggest antitrust trial in nearly 25 years kicks off on Tuesday as the Justice Department makes its case that Google is an illegal monopoly.

Questions about the direction of U.S. foreign policy as the State Department operates without a full complement of staff are expected at the deputy secretary of state nomination hearing for John Sullivan.

On this date in 1961 John F. Kennedy made, at the time, a stunning announcement. And in 1968, a 630-foot stainless steel structure in St. Louis was...

Intel’s plan to build a massive computer chip manufacturing complex in New Albany offers a glimpse of what’s next for Ohio’s economic future. Could Ohio move from the buckle of the rust belt to the hub of the Silicon Heartland?

St. Paul & the Broken Bones bring the grooves and the moves to the ACL stage.

Appraisal: Martin Schongauer St. Lawrence Engraving, ca.1485

Appraisal: 1879 Augustus St. Gaudens Relief Plaque, in Vintage Portland.

=St. Louis combats opioid crisis as overdose deaths skyrocket among Black Americans

USA Today's Yamiche Alcindor discusses the St. Louis County's juvenile justice system.

The history of St. Marks AME Church in Queens, NY reveals some 160-year old insight.