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The FDA says esketamine, an antidepressant derived from the anesthetic and party drug ketamine, can now be prescribed on its own. It was approved in 2019 to treat severe depression.

Your one-stop guide to the year in arts and culture, from binge-worthy shows to hundreds of books recommended by NPR staff and a playlist of the 124 best songs of 2024.

The 84-year-old is "on the mend" after she underwent surgery for a hip injury she sustained during a congressional trip to Luxembourg, a spokesperson said.

The 78-year-old former president was discharged from a Washington hospital on Tuesday and will be home for Christmas after he was admitted the day before with a fever.

A vehicle drove into a crowd on New Orleans' famed Canal and Bourbon Street in the first hours of New Year's Day. The FBI is investigating the incident.

The World Health Organization Director-General Tedros Adhanom Ghebreyesus says he and colleagues "escaped death narrowly" when an Israeli airstrike targeted Yemen's main airport.

2024 was a year of breakthroughs, with new stars storming the top of the charts and artists across genres making modern classics. NPR Music's list of best songs of the year has something for everyone.

John Ratcliffe, former director of national intelligence during President Trump's first term, has been confirmed by the Senate to lead the CIA — the first person to have held both jobs.

DOJ had already dropped the case against Trump. Now a federal appeals court has formally dismissed the remainder of that case against Trump's valet Walt Nauta and property manager Carlos De Oliveira.

In some parts of the Plains region, the National Weather Service expects temperatures to reach as low as the negative 20s and 30s.