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Three decades ago, Congress set up a system to encourage drug companies to develop treatments for rare diseases. The law has worked, but at a high cost.

Hundreds of NPR readers recounted their first memory of a news event. These are some of their stories.

Monty Python’s Eric Idle is still "Always Looking on the Bright Side of Life." He’s out with a "sortabiography" and joins us.

Lage began playing guitar at the age of 5 and appeared on stage at the Grammys at 13. He talks to Fresh Air about growing up a guitar prodigy, his father's gentle coaching and his new trio album.

Columbus airport security Sargenat Scott Bedham says bomb-sniffing dogs will be used to screen for explosives at the city's two major airports. Bedham…

In her new cookbook, Nothing Fancy, Alison Roman is rebranding how we think of having people over for dinner. You don't have to prepare a picture perfect moment to share a good meal with friends.

Singer and dancer Johnny Clegg — the co-founder of two groundbreaking, racially mixed bands during the apartheid era — is battling pancreatic cancer. He's saying goodbye to his fans on a U.S. tour.

Lawmakers are already setting their sights on 34 Senate seats that will open up in 2024, indicating a busy election season.

Meridah Nandudu was a single mom of two kids, unemployed and in despair. Then she had an idea: Maybe the "humble" coffee beans she'd grown up with on her parents' farm could lead her to a better life.

Jewish members of Germany's far-right party are launching a group called "Jews in the AfD." The group insists that claims about the AfD's anti-Semitism are exaggerated.