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Initial reports suggest the trailer was headed east on I-40 when one of its tires blew out, causing the driver to lose control and sending the truck careening across the median into oncoming traffic.

America's top orchestras are programming little or no music by women. Philadelphia has now included two works by female composers. A month ago it had zero.

Ohio State coach Urban Meyer addressed speculation that he could step down at the end of the season, saying Monday he felt fine and definitely would be…

Six of 10 U.S. Catholics say Pope Francis is doing only a "fair" or even a "poor" job handling the clergy abuse crisis. He is now only as popular as his predecessor, Pope Benedict.

The Food and Drug Administration typically follows the advice of its expert advisers. A quick agency decision on the Johnson & Johnson vaccine is expected given the state of the pandemic.

Cleveland was seeking its first five-game winning streak since 2018, which was the final season of LeBron James’ second stint with the franchise.

The latest version of NPR's mobile news application can be controlled using your voice in some Ford vehicles.

The 24 victims included seven children and 13 women. Authorities were still carrying out autopsies and waiting for next of kin to identify the victims.

And spending by groups supporting Democratic incumbent Sen. Raphael Warnock has more than doubled contributions from groups backing Republican challenger Herschel Walker.

AAA predicts some 55.4 million Americans will flock to holiday destinations in the third-busiest Thanksgiving travel season, since the organization started keeping track in 2000.