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"Because you have the right to have a Secretary of Defense whose views are better aligned with yours ... I believe it is right for me to step down from my position," Mattis wrote to the president.

Ohio State is seeking its first visit to the Final Four since 1993.

President Biden approved a federal disaster declaration for Mississippi. Officials said dozens were injured, while hundreds were displaced. More bad weather is expected in the Southeast into Monday.

Caleb Anderson is a sophomore at Chattahoochee Technical College in Marietta, Ga. He's taking calculus and macroeconomics and wants to be an aerospace engineer to help "people reach the stars."

In 2012,Saturday Night Live's Bill Hader told Fresh Air that watching old films as a child sparked his interest in Hollywood. His latest project is the HBO series Barry.

Before he wrote comic books and advertising, Chad Lambert was living his dream – and it nearly killed him. Lambert was a radio host-producer for several...

The attack at a Florida nightclub played out for more than three dramatic hours. Survivors, doctors and law enforcement officials recap the deadliest mass shooting in modern U.S. history.

Norishige Kanai said he had grown up to 3 1/2 inches since arriving in space, sparking worry about whether he'd fit in the spacecraft home. Turns out, Kanai did grow, just not that much.

From Renaissance still lifes of fruit to Andy Warhol's soup cans, there is a long tradition of artists celebrating food. But here in Northeast Ohio, there is a food-and-art collaboration unlike any other.

It hasn’t happened often since former Ohio governor Ted Strickland and Cincinnati council member P.G. Sittenfeld began running against each other for...