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Biden and Trump will hold their first presidential debate tonight. Scientists think understanding how the brain removes waste and toxins may help treat a broad range of disorders.

The sale caps a dizzying saga for Twitter and Elon Musk, the world's richest man and a prolific user of the social media platform.

As Ohio's summer season begins, the visibility of those who are unhoused increases. Many people who lack access to heat management conditions in residencies, restaurants or offices opt to use outdoor public spaces.

The U.S. government accused Russia of trying to interfere with this year's elections and announced new steps to counter those actions.

Kids may be little. But the cost of paying for someone to take care of them is really big. Stressed-out parents are pinching pennies, driving for Uber and putting off saving and having more kids.

NPR has identified nearly 40 small, independent entities – both inside and outside the federal government's control – that a team of young DOGE staffers has tried to access in recent weeks.

As we wrap up this year, we look back at an eventful year through the lenses of NPR member and affiliate stations. We asked photographers to share memorable events they covered throughout 2022.

Democrats are aiming to make gains in North Carolina in 2024. And that path to victory in the state runs through its small towns and youngest voters. Here's where some of them stand.

The federal government is preparing to shed up to a quarter of its 360 million square feet of real estate, an NPR analysis finds. The agency in charge of federal real estate is also slashing staff.

We asked around the newsroom to find favorite nonfiction from the first half of 2024. We've got biography and memoir, health and science, history, sports and much more.