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After a week of high drama, another played out in the early hours of Friday with Sen. John McCain joining two moderate Republicans, two independents and every Democrat in voting against the bill.

Secretary of State Rex Tillerson said this week the U.S. is not seeking a regime change in North Korea. That's in contrast to CIA Director Mike Pompeo, who suggested last month that he would like to see Kim Jong-un removed from power. Former diplomats say it's the latest example of a less-than-coherent Trump administration foreign policy, where it's not clear who's in charge.

Rachel Martin talks to former U.N. ambassador and diplomatic negotiator Bill Richardson about the limits of diplomacy and international law when dealing with Pyongyang.

Irma tore through the U.S. Virgin Islands, leaving thousands displaced and billions of dollars of property destroyed. Gov. Kenneth Mapp of the U.S. Virgin Islands talks about the recovery efforts.

Following an investigation by Kaiser Health News and NPR, the Food and Drug Administration has moved to close a loophole that lets drugmakers skip pediatric testing of drugs to treat rare diseases.

Tunisia's president is pushing for his country to become the first in the Arab world to ensure equality between men and women in inheritance laws. Currently, a man's share equals that of two women.

Raila Odinga said he's mounting a legal challenge to what he calls President Uhuru Kenyatta's "computer-generated fraud." But he's not the only one to raise questions about the election recently.

NPR's Ari Shapiro speaks with Ambassador Robert Gallucci, chairman of the U.S.-Korea Institute at Johns Hopkins, about North Korea's invitation to President Trump to meet. He was chief negotiator during the North Korean nuclear crisis of 1994, and has been involved in informal talks with North Korean officials.

As the administration seeks to redo the North American Free Trade Agreement, the industry is watching the talks closely. Automakers say changes could drive up costs, making them less competitive.

Rachel Martin talks to Democratic Sen. Richard Blumenthal of Connecticut about the White House invitation to members of Congress to come talk about measures that could prevent gun violence.